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cobicistat will raise the stage or effect of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.elvitegravir/cobicistat/emtricitabine/tenofovir DF will increase amounts of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism.nifedipine will increase the level or impact of bortezomib by impactin

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